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Senior Staff High Performance Computing Engineer

Company: Guardant Health
Location: Redwood City
Posted on: June 23, 2022

Job Description:

Company DescriptionCompany DescriptionGuardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360 -, Guardant360 CDx and GuardantOMNI - tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection.Job DescriptionGuardant's HPC team builds and operates the computational technology backbone of the company.This includes scalable data storage that holds PBs of genomics data, high performance compute clusters running a custom bioinformatics pipeline in production and R&D environments, and the software infrastructure that hosts an ecosystem of services for internal data processing and external data integration. To facilitate Guardant Health's fast growth in the next few years, the HPC team is looking for a strong technical engineer who can help maintain and help grow the HPC infrastructure during its aggressive expansion, while working with corporate IT, SQA and DevOps/SRE teams.This role can be remotely worked part-time, but requires a very hands-on on, on-premise presence when on rotation, minimally. In this role, you will primarily:

  • Help manage multiple HPC clusters and cluster file systems.
  • Identify, select, qualify, and operationalize most efficient, effective Server hardware.
  • Help research, develop, and implement the next generation HPC solution.
  • Troubleshoot the production system stack down to source code level e.g., shell scripts, python and others.
  • Collaborate regularly with internal teams and key stakeholders to understand requirements, cost-optimize solutions, and build knowledge of major workloads and technologies.
  • Maintains, monitors, and supports the infrastructure environment and/or facilities.
  • Used and maintained enhanced production monitoring and additional capability.
  • Review and validate hardware failure data as part of qualification process.
  • Support improvements for increased system reliability and performance.
  • Supports in a senior role multiple systems or applications of medium to high complex (complexity defined by size, technology used, and system feeds and interfaces) with multiple concurrent users, ensuring control, integrity, and accessibility.
  • Work with offsite consultants to maintain the infrastructure.
  • Work with vendors to troubleshoot, upgrade and repair systems as needed.
  • Participate in a 24/7 on-call rotation.About You:You enjoy an agile, very fast paced and highly technical environment. You are a self-driven accomplished technologist who strives to be ever improving your skills, value to the company and improve the computational infrastructure. You are dedicated to engineering excellence yet pragmatic and flexible. You have the ability to maintain the day-to-day support SLA while running various key projects that move the business forward.
    • 6+ years of Linux/Unix administration, knowledge of Unix network protocols, TCP/IP network fundamentals, core infrastructure technologies and virtualization
    • 6+ years of large-scale data storage and compute clusters (HPC) infrastructure
    • 4+ years working in and with on-premises and cloud-based (AWS, Google, IBM and Azure) datacenters.
    • 3+ years of building software release and ops processes and automation toolset
    • 5+ years providing documentation of system administration.QualificationsFollowing Skills Sets are Preferred:
      • Experience administering IBM's General Parallel File System
      • Experience administering Grid Engine scheduler
      • Experience with using Bright Cluster Manager
      • Experience with cloud bursting technologies
      • Experience with wide area file systems
      • Experience with docker and container technologies
      • Experience with Kubernetes, preferably with Certified Kubernetes Administrator (CKA, up to date)
      • Operating infrastructure compliant with HIPAA and SOX standardsEducationB.S. in Computer Science or related fieldAdditional InformationEmployee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.All your information will be kept confidential according to EEO guidelines.To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job ApplicantsPlease visit our career page at:

Keywords: Guardant Health, Redwood City , Senior Staff High Performance Computing Engineer, Engineering , Redwood City, California

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