Senior Engineer 1 / 2
Company: Adicet Bio, Inc.
Location: Redwood City
Posted on: May 21, 2023
Job Description:
Senior Engineer 1 2 - Careers At Adicet Bio Back To Openings
Senior Engineer 1 / 2 Department: Cell Therapy Mfg Ops Location:
Redwood City, CA
START YOUR APPLICATION JOIN US! Adicet Bio, Inc. is a clinical
stage biotechnology company discovering and developing allogeneic
gamma delta T cell therapies for cancer. Adicet is advancing a
pipeline of "off-the-shelf" gamma delta T cells, engineered with
chimeric antigen receptors (CARs) and adaptors (CAds), to enhance
selective tumor targeting and facilitate innate and adaptive
anti-tumor immune response for durable activity in patients. For
more information, please visit our website at
https://www.adicetbio.com . SENIOR ENGINEER 1 / 2 This is a
lab-active role in the Manufacturing Sciences and Technology group
focusing on the development of the at-scale manufacturing process
of Adicet's gamma delta T cell products with opportunities to
participate in tech transfer to support cGMP manufacture.
Responsibilities:
- Lead and/or execute studies to scale-up CAR T manufacturing
processes based on the gamma delta T cell platform using different
bioreactor platforms.
- Design and execute cell culture-based experiments utilizing
novel technologies to optimize platform processes with closed
systems with a focus on scale-up of an allogenic cell therapy.
- Create improvements to platform process for activation,
transduction, and expansion unit operations.
- Perform multi-color flow cytometry acquisition and
analyses.
- Tracking and ordering requisite consumables for PD and MS&T
subteams
- Manage Technology Transfer activities including batch record,
SOP, work instruction, and protocol authorship.
- Serve as a subject matter expert and provide technical insights
and support in troubleshooting and root cause investigations.
- Manage 1-2 direct reports.
- Accurately compile data in electronic notebook entries and
aggregate data files Qualifications:
- BS/MS/PhD in Biochemical Engineering, Chemical Engineering,
Science or Biotechnology.
- BS with 10+ years or MS with 8+ years' experience in industry
setting or PhD with 4+ years of relevant cell therapy
experience.
- A strong background in cell therapy or CAR T products
required.
- Experience with evaluating and developing processes on
bioprocess equipment such as Sefia, Rotea, Sepax, LOVO, CliniMACS
Prodigy, Xuri, or Sartorius bioreactors.
- Experience with GMP processing and/or tech transfer related
activities
- Experience in aseptic technique, cell culture, and retroviral
or lentiviral transductions
- Expertise with multi-color flow cytometry for T cells
- Expertise with Microsoft Office suite, JMP, Prism, FlowJo,
Benchling (or other electronic lab notebook software)
- Conduct and provide help to the team members with analysis and
reporting results, and interpretation of data.
- Possesses good verbal and written communication skills.
- Ability to operate in a fast paced, industrial environment. At
Adicet, our people are our greatest focus. We believe that
attracting and retaining the best and brightest is the key to
achieving our mission to deliver best-in-class gamma delta T cell
therapies for patients fighting cancer. We offer a competitive
compensation package including base salary, annual cash bonus,
long-term incentives (equity), Employee Stock Purchase Plan (ESPP)
and a 401(k) with ROTH and a 4.5% Company match. To ensure the
wellness of our employees and their loved ones, we offer
comprehensive health plans (medical, dental, vision, etc.),
Flexible Health and Commuter Spending Accounts (FSA) and a company
matched Health Savings Account (HSA). We also offer a life,
AD&D, short and long-term disability insurance, and legal, pet,
and various other voluntary insurance programs. We also believe our
greatest ideas come when we are refreshed and focused, and we offer
generous paid time-off including 12 company holidays with
end-of-year shutdown, vacation, sick time, and paid parental leave.
Adicet is located in a state-of-the-art facility and works to
create an incredible office experience with an onsite gym and
various other fitness options, abundant, zero-cost, onsite parking
with electric vehicle charging stations and free shuttle
(Caltrain), company subsidized lunches (delivered onsite daily) and
fully stocked breakrooms. In compliance with California's pay
transparency law and in pursuit of pay equity and fairness, we
publish salary ranges for all open positions. The pay scale range
for this role is $120,000.00 - $166,000.00 annualized base salary.
The salary of the finalist selected for this role will be set based
on a variety of factors, including but not limited to, their
qualifications (education, experience, specialty, and training),
and peer and market data. This listed salary range represents the
Company's good faith and reasonable estimate of the range of
possible compensation at the time of posting. START YOUR
APPLICATION
Keywords: Adicet Bio, Inc., Redwood City , Senior Engineer 1 / 2, Engineering , Redwood City, California
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