Software Engineer II
Company: Guardant Health
Location: Redwood City
Posted on: January 16, 2022
Guardant Health is a leading precision oncology company focused on
helping conquer cancer globally through use of its proprietary
blood tests, vast data sets and advanced analytics. The Guardant
Health Oncology Platform leverages capabilities to drive commercial
adoption, improve patient clinical outcomes and lower healthcare
costs across all stages of the cancer care continuum. Guardant
Health has launched liquid biopsy-based Guardant360 -, Guardant360
CDx and GuardantOMNI - tests for advanced stage cancer patients.
These tests fuel development of its LUNAR program, which aims to
address the needs of early stage cancer patients with neoadjuvant
and adjuvant treatment selection, cancer survivors with
surveillance, asymptomatic individuals eligible for cancer
screening and individuals at a higher risk for developing cancer
with early detection
The successful Software Engineer II candidate will join an
interdisciplinary team working with an unprecedented set of
clinical DNA whole genome and exome sequence data and multiple
epigenetic data types produced by novel R&D pipelines at
Guardant Health. The scope of this project provides unique
opportunities for developing and learning novel analytical methods
for DNA sequencing data, including cell free DNA-based transcript
expression and methylation data integrated with epigenetic data
This individual will work with software engineers, bioinformatics
scientists, assay developers, and project leaders to ensure the
quality of bioinformatics software used in CLIA, CAP, NYDOH, and
FDA regulated environments and the correct installation on
Essential Duties and Responsibilities:
- Design and Implement algorithm software pertain to
classification and analysis of anomalies related to early
indication of cancer.
- Conduct software design reviews, communicates results through
presentations and project reports as well as scientific
- Work with large, complex data sets. Tend to non-routine
analysis problems, applying deep epigenetic knowledge to conduct
end-to-end analysis of epigenetic cell free nucleic acid NGS
- Leads other scientists and engineers for research
- Provide analytic support on individual samples and research
- Provide analytic support to CLIA and CAP regulated clinical
- Explore genomic data from clinical patients and external
annotation sources to enhance quality of reporting.
- Develop scripts for research and development activities.
- BS. or higher agree in Bioinformatics, Computational Biology,
Statistics, Biological Sciences, Cancer Biology, Genetics,
Genomics, Computer Science. Equivalent industry experience
- 4+ Years industry experience including experience with a
programming language such as R and Python.
- Deep understanding with next generation sequencing data
analysis (DNA, RNA, or epigenetic analysis). Experience with modern
tools and pipelines in genomics for processing and analysis of
primary data, including somatic and structural variant
- Demonstrated effective written and verbal communication
- Excellent organizational and people skills with the ability to
work across functions.
Experience in one or more of the following is a plus:
- Hands on knowledge of docker applications and CI tools such as
- Proficient in Linux base environment and Bash scripting.
- Experience working in a regulated environment (CLIA, CAP,
NYDOH, and FDA).
Covid Vaccination Policy: Starting January 7, 2022, Guardant Health
will require all employees to be fully vaccinated to either (a)
establish that they have been fully vaccinated against COVID-19; or
(b) request and obtain an approved exemption from Guardant's
COVID-19 U.S. Vaccination Policy as a reasonable accommodation, as
consistent with applicable laws. An employee is considered fully
vaccinated against COVID-19 two weeks after receiving the second
dose of a two-dose vaccine or one dose of a single-dose
vaccination. Acceptable vaccines are approved or under emergency
use authorization by the U.S. Food and Drug Administration (FDA)
and/or the World Health Organization (WHO). In addition,
fully-vaccinated employees will be required to maintain their
fully-vaccinated status under this policy by obtaining, if
applicable, any FDA-approved boosters.
Employee may be required to lift routine office supplies and use
office equipment. Majority of the work is performed in a
desk/office environment; however, there may be exposure to high
noise levels, fumes, and biohazard material in the laboratory
environment. Ability to sit for extended periods of time.
Guardant Health is an Equal Opportunity Employer. All qualified
applicants will receive consideration for employment without regard
to race, color, religion, sex, sexual orientation, gender identity,
national origin, or protected veteran status and will not be
discriminated against on the basis of disability.
All your information will be kept confidential according to EEO
To learn more about the information collected when you apply for a
position at Guardant Health, Inc. and how it is used, please review
our Privacy Notice for Job Applicants.
Please visit our career page at:
Keywords: Guardant Health, Redwood City , Software Engineer II, IT / Software / Systems , Redwood City, California
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