Senior Scientist, Sustain & Support

Company: Guardanthealth
Location: Redwood City
Posted on: September 17, 2020

Job Description:

Full-time

Company Description Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. Its Guardant Health Oncology Platform is designed to leverage its capabilities in technology, clinical development, regulatory and reimbursement to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs. In pursuit of its goal to manage cancer across all stages of the disease, Guardant Health has launched multiple liquid biopsy-based tests, Guardant360® and GuardantOMNI® , for advanced stage cancer patients, which fuel its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection. Since its launch in 2014, Guardant360® has been used by more than 7,000 oncologists, over 50 biopharmaceutical companies and all 27 of the National Comprehensive Cancer Network centers.

Job Description To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Scientist to lead the execution of sustaining and troubleshooting activities pertaining to our launched assays for rare variant studies with next-generation sequencing. At Guardant, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.

Duties and Responsibilities:

Identify areas for improvement in assay and propose and implement solutions

Design and perform experiments to continually improve our assay workstreams

Develop and perform longitudinal analytics of clinical lab performance and provide regular updates to cross-functional teams

Write experiment reports and update SOPs as needed

Collaborate cross-functionally with operations, process engineering, and bioinformatics to facilitate effective delivery sustaining and support deliverables

Lead in troubleshooting efforts with our Operations teams and capture lessons learned

Manage the escalation process between Operations and Technology teams

Conceptualize and perform feasibility studies on new assay improvements

Ensure all work is performed and documented in compliance with applicable regulatory and quality practices (FDA, ISO13485)

Be a mentor to grow junior team members

Present data, proposals, and progress in various forums and to technical and non-technical audiences

Qualifications Required Skills:

PhD degree in molecular biology, biomedical sciences, bioinformatics, genetics, biochemistry, or related field

Strong foundation in molecular biology techniques and NGS assay development, exemplified by publications, patent applications, or previous product development experience

Strong data analysis skills with experience with Python and R and the experience in handling large datasets

Demonstrated ability to organize, document and communicate scientific data

Consummate team player: demonstrated ability to contribute in an environment where numerous contributions are required to accomplish complex goals. Enjoy working independently and collaboratively in a fast-paced environment and able to adapt to change

Highly motivated and responsible self-starter and independent problem solver

Curiosity and drive

Preferred Skills:

3+ years of industry work experience preferred

Product development in a regulated environment

Experience with assay development for automated liquid handling platforms

Experience in sustaining development or support

Additional Information Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our  Privacy Notice for Job Applicants .

Keywords: Guardanthealth, Redwood City , Senior Scientist, Sustain & Support, Other , Redwood City, California