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Scientist , Formulation Development

Company: AbbVie
Location: Redwood City
Posted on: November 20, 2020

Job Description:

AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. AbbVie is also expanding their expertise through partnering with companies leading the way in emerging biologic technologies including oncolytic virus--- and CAR-T cells. We have an exciting opportunity available for Scientist I within the Pharmaceutical Development Group in the CMC Biologics department at AbbVie, Redwood City, CA. AbbVie at Redwood City is an R&D organization focused on development of innovative biologics in the field of Oncology. This position will support CMC drug product development for oncology pipeline that include mAbs, ADCs, and novel bispecific antibody formats, through clinical proof-of-concept. Key responsibilities include: Conduct stability studies to enable selection of formulation composition and container closure for liquid and lyophilized dosage forms for antibody therapeutics Conduct drug product process development studies as well as product end-use studies to guide dose solution administration Provide data analysis and documentation for technical reports, presentations, and regulatory filings Qualifications EDUCATION and/or EXPERIENCE BS or MS degree in pharmaceutical sciences, chemical engineering, analytical sciences, or equivalent field with 3-7 years of relevant experience in the biotechnology industry. Strong technical background encompassing protein chemistry coupled with an understanding of CMC development workflows and requirements Hands-on experience with analytical techniques for protein characterization and stability testing required Prior protein formulation development and lyophilization process development experience highly preferred Excellent communication and written skills required

Keywords: AbbVie, Redwood City , Scientist , Formulation Development, Other , Redwood City, California

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