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Research Investigator 1, Protein Mass Spectrometry

Company: Bristol-Myers Squibb
Location: Redwood City
Posted on: February 23, 2021

Job Description:

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.--In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Please Note - We are restarting our search for the Research Investigator 1 as of 12/2/20! The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as antibodies and endogenous proteins in order to optimize their utility as therapeutic agents. We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit. Position Summary We are seeking a skilled and enthusiastic Scientist to join our Protein Analytics Group. Your primary responsibilities will be to characterize the primary, tertiary, and quaternary protein structure using a variety of characterization techniques such as mass spectrometry, liquid chromatography, and other analytical techniques. Additional responsibilities will include performing mass spectrometry-based proteomics studies and characterization of post-translational modifications for target discovery and other applications. You may also represent the group at discovery team meetings for a variety of oncology projects, where you contribute with your protein characterization expertise to the selection and optimization of our therapeutic antibodies. Responsibilities
--- Develop and run multiple types of protein characterization assays such as LC-MS, SEC-MALS, glycan analysis, amino acid concentration, etc.
--- Conduct mass spectrometry-based proteomics studies
--- Present data and analysis in written and oral form to project leaders and teams
--- Collaborate closely with Biology, Hybridoma and Protein Engineering groups
--- PhD with 2 - 5 years, Masters with 7+ years or B.S. with 10 + years industrial and/or relevant experience in Chemistry, Biochemistry, Biophysics, or a related field
--- Expertise in characterizing protein structure including molecular weight, aggregation state, glycan structure, etc.
--- Experience with protein mass spectrometry
--- Experience with SEC, HLIC, RP chromatography
--- Strong attention to detail and excellent bench skills a must --- Candidates possessing strong skills with data analysis including software and algorithm development will be highly preferred --- Excellent written and oral communication skills
--- Excellent time management and organizational skills
--- Ability to contribute to multidisciplinary discovery teams Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. We're a community of women leveraging our connections into top companies to help underrepresented women get the roles they've always deserved. Simultaneously, we work to build truly inclusive hiring processes and environments where women can thrive and not just survive. Are you hiring? Join our platform for diversifiying your team Help us improve by sharing your feedback. Thank you for sharing your feedback with us! How would you rate your experience? Hate Dislike Like Love Select an element on the page. Enter your email address if you would like to receive a follow up. Thank you for sharing your feedback with us! Thank you for sharing your feedback with us!

Keywords: Bristol-Myers Squibb, Redwood City , Research Investigator 1, Protein Mass Spectrometry, Other , Redwood City, California

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