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Pilot Plant Development Associate, Upstream (contract)

Company: Adverum Biotechnologies
Location: Redwood City
Posted on: May 3, 2021

Job Description:

Pilot Plant Development Associate, Upstream (contract)

Redwood City, CA /

Technology Development Manufacturing Sciences & Technology /

Adverum is looking for a Pilot Plant Development Associate, Upstream (contract) to join our team in Redwood City. This position reports into Technical Development Scientist II. This individual will be a key member of the Pilot Process Development Team, focusing on upstream cell culture activities.

This is a 6mo contract to start.

What you'll do:
Work closely with team members to perform Cell Culture maintenance and passaging in shake flasks, small-scale, pilot scale/Manufacturing scale Bioreactor. Set-up, maintain and clean required upstream equipment. Follow good documentation practices to maintain accurate records through a highly organized lab notebook and/or in a Batch Record. Ensure safe workplace in compliance with the company and EHS' rules and regulations. Assist in the planning and manufacturing of AAV based viral vectors for development use encompassing the entire upstream process from thaw to harvest. Work to evaluate process changes with the goal of optimizing the existing upstream AAV process to enhance robustness, scale-ability, and/or yield Work to identify optimize, revise, and update current process batch records, protocols, and procedures to make them more robust and streamlined. Assist in maintaining laboratory equipment. Other responsibilities may be assigned as needed.
About you:
Bachelors degree (biology, chemistry, etc) with minimum 1-2 years of experience in a cell culture laboratory Proficient in general and non-routine laboratory skills including aseptic technique, multi-channel pipetting, and dilution calculations to perform basic cell culture activities. Experience in handling shake flask is a must. Requires some knowledge of GxP standards, and the ability to apply compliance principles to Adverums laboratory practices. Able to work in a fast-paced environment as a team player with effective communication skills. Excellent computer skills; especially proficient in Excel and Word. Strong desire to learn new technologies, skill sets, and the science behind AAV processing. Strong teamwork and communication skills. About Us
Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. Adverums core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.

At Adverum,InclusionandDiversityare at our core. We believe in the power of being your authentic self. We strive to create the space which allows for everyone in our AdverumCommunityto not only feel safe but encouraged to speak, learn from each other, grow in their professions and be the very best versions of themselves no matter what their age, ethnic background, gender, origin, religion or sexual orientation

Keywords: Adverum Biotechnologies, Redwood City , Pilot Plant Development Associate, Upstream (contract), Other , Redwood City, California

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