At Bristol Myers Squibb, we are inspired by a single vision -
transforming patients' lives through science. In oncology,
hematology, immunology and cardiovascular disease - and one of the
most diverse and promising pipelines in the industry - each of our
passionate colleagues contribute to innovations that drive
meaningful change. We bring a human touch to every treatment we
pioneer. Join us and make a difference.
We are looking for a highly motivated and enthusiastic scientist
with deep expertise in antibody discovery through Single B-Cell
technologies to join the Antibody Generation group within the
Biotherapeutics department in Redwood City, CA This is an exciting
opportunity to make a significant impact within a department that
is driving the biologics pipelines in Bristol Myers Squibb. The
candidate must have in-depth knowledge of current state-of-the-art
antibody generation through high-throughput B cell platforms and
preferably prior expertise in antibody library display technologies
and be able to apply these practices at the bench. He will drive
technology developments and optimization of innovative discovery
technologies, such as single B cell cloning, associated platforms,
and possibly display, to expedite the process and deliver high
quality lead antibody candidates.
+ Contribute to optimize the existing single B cell cloning
capacity within the Antibody Generation group. Expand the scope of
applications of single B cell protocol and harmonize it with
associated supporting platforms in close collaboration with other
groups across the department.
+ Fully integrate the single cell sorting, cloning, recovery and
sequencing protocols into the lead generation pipeline.
+ Proactively evaluate new technologies, instrumentation, and
assays available from the literature or scientific meetings to
improve in-house platforms.
+ Use B-cell immortalization methods and combine with display
technologies (yeast and/or phage) to identify antibody hits against
soluble or complex membrane targets.
+ Be a champion in the lead discovery process and collaborate
with biology project leaders closely to advance innovative
therapeutics from Discovery to Development.
+ Stay informed and contribute to the vision in the technology
development space especially in single cell analytics and gene
+ Excellent written and oral communication skills are necessary
in order to succeed in the BMS cross-functional scientific
+ Multitask and accomplish goals under project team
+ Ph.D. in molecular biology or immunology or related field
followed by a 2+ years industry or postdoctoral academic experience
or M.Sc. degree followed by more than 10 years of industry and/or
academic experience is required
+ Experience in antibody generation through Single B-cell
cloning is highly desired
+ Previous industry or academic work using antibody phage and/or
yeast display libraries is highly desired
+ Proficiency in cell biology skills such as FACS.
Target-centric cell sorting or selection experience.
+ High proficiency in all critical molecular biology techniques
with focus on high throughput, high sensitivity gene rescue from
single cells or tissues of interest.
+ Proficiency in large dataset analysis preferred
+ In-depth knowledge of B/T cell biology and humoral and cell
mediated immune responses.
+ Highly innovative and self-motivated.
+ Excellent time management and organizational skills.
+ Demonstrated ability to work in a multidisciplinary biologics
Around the world, we are passionate about making an impact on
the lives of patients with serious diseases. Empowered to apply our
individual talents and diverse perspectives in an inclusive
culture, our shared values of passion, innovation, urgency,
accountability, inclusion and integrity bring out the highest
potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and
flexibility in our work environment. We offer a wide variety of
competitive benefits, services and programs that provide our
employees with the resources to pursue their goals, both at work
and in their personal lives.
Our company is committed to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace adjustments and ongoing support in their
roles. Applicants can request an approval of accommodation prior to
accepting a job offer. If you require reasonable accommodation in
completing this application, or any part of the recruitment process
direct your inquiries to firstname.lastname@example.org. Visit
careers.bms.com/eeo-accessibility to access our complete Equal
Employment Opportunity statement.
**Company:** Bristol Myers Squibb
**Req Number:** R1538875
**Updated:** 2021-04-23 01:29:06.458 UTC
**Location:** Redwood City,California
Bristol Myers Squibb is an equal opportunity employer. Qualified
applicants will receive consideration for employment without regard
to race, color, religion, sex, sexual orientation, gender identity,
national origin, age, disability, protected veteran status,
pregnancy, citizenship, marital status, gender expression, genetic
information, political affiliation, or any other characteristic
protected by law.