At Bristol Myers Squibb, we are inspired by a single vision -
transforming patients' lives through science. In oncology,
hematology, immunology and cardiovascular disease - and one of the
most diverse and promising pipelines in the industry - each of our
passionate colleagues contribute to innovations that drive
meaningful change. We bring a human touch to every treatment we
pioneer. Join us and make a difference.
The Tumor Microenvironment Thematic Research Center (TME TRC) is
focused on developing therapeutic targets at the intersection of
tumor, stromal and immune biology within the TME with the goal of
enhancing responsiveness to checkpoint blockade and targeted
therapies. Comprising of scientists across multiple disciplines we
are responsible for the biology and translational science necessary
to support drug development from target identification through to
first in human studies.
The Principal Scientist will join the Cancer Biology research
team within the Tumor Microenvironment Thematic Research Center
(TME TRC) at Bristol-Myers Squibb (BMS) in Redwood City, CA. This
team is composed of cancer biologists/cancer geneticists who work
closely with immunologists/immuno-oncologists and stroma biologists
focused on developing therapeutic targets integrated across the
tumor microenvironment. Our mission is to provide transformative
therapeutics to cancer patients that improve response rates and
durability to this challenging disease.
The qualified candidate is a highly motivated, interactive, and
creative individual who possesses substantial experience in
studying tumor biology and genetics. The candidate should have been
exposed to or have experience leading pre-clinical drug discovery
programs in an industry setting. The candidate will also be
expected to contribute to the team's project portfolio by
developing new project hypotheses (gleaned from literature reports,
evaluation of public and proprietary tumor profiling datasets,
pre-clinical mechanistic models and functional screens, etc.),
validating the hypothesis in pre-clinical models, developing
translational hypothesis to guide their clinical application and
develop assays to support early pre-clinical drug development. The
successful candidate will manage 2-3 technical associates that
provides a "lead in the laboratory" opportunity to mentor excellent
science and technical development of these associates. S/he will
keep up-to-date in the literature related to his/her field, act as
an expert resource in his/her scientific field and in related
The ability to design and execute decision driving experimental
and strategic plans to advance portfolio projects is required, as
is a demonstrated proficiency in the use of informatics tools and
translational profiling data. To be successful, the candidate must
possess proficiency in verbal and written communication, capable of
presenting scientific results to multidisciplinary teams, senior
management and at external scientific meetings. As we work in a
highly matrixed environment, the candidate will also need to be
influential and effective in sharing ideas and advice across the
site (as well as across the company) to drive innovation to advance
our portfolio and to work effectively with all relevant and
necessary functions within BMS.
A Ph.D. degree with a minimum of 3-5 years of Industry
experience in cancer biology and genetics or a closely related
field is required.
Experience/exposure to preclinical drug development in an
industry setting, especially in small molecule drug discovery.
A proven track record in the field of cancer biology and
genetics, as evidenced by publication record is required.
Excellent in vitro biology skills, experimental design, and
execution is required, as is expertise to independently apply
bioinformatics and data mining through multi-variate analysis.
Ability to effectively interact with core bioinformatics
colleagues, as well as to use desktop tools/interfaces (e.g.,
Oncoland, Wuxi) and public databases (CBIO, Achilles, etc.) is
Experience in the design, validation, and execution of genetic
and/or phenotypic screens is desired.
Excellent interpersonal skills with the ability to interact
effectively to influence people, internally and externally, is
The ability to manage a small laboratory group is expected,
including providing growth and development opportunities for
- This position is located in Redwood City, CA. There will be
less than 10% travel.
Around the world, we are passionate about making an impact on
the lives of patients with serious diseases. Empowered to apply our
individual talents and diverse perspectives in an inclusive
culture, our shared values of passion, innovation, urgency,
accountability, inclusion and integrity bring out the highest
potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and
flexibility in our work environment. We offer a wide variety of
competitive benefits, services and programs that provide our
employees with the resources to pursue their goals, both at work
and in their personal lives.
Our company is committed to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace adjustments and ongoing support in their
roles. Applicants can request an approval of accommodation prior to
accepting a job offer. If you require reasonable accommodation in
completing this application, or any part of the recruitment process
direct your inquiries to email@example.com. Visit
careers.bms.com/eeo-accessibility to access our complete Equal
Employment Opportunity statement.