Sr. Investigational Computational Biologist
Location: Redwood City
Posted on: May 3, 2021
Sr. Investigational Computational Biologist
Karius is a venture-backed life science startup that is
transforming the way pathogens and other microbes are observed
throughout the body. By unlocking the information present in
microbial cell-free DNA, we're helping doctors quickly solve their
most challenging cases, providing industry partners with access to
the microbial landscape to accelerate biomarker discovery and
clinical trials, discover novel microbes, to ultimately reduce
patient suffering worldwide.
We are seeking a candidate to work in a rapid, iterative research
environment at the interface of our analytics, molecular biology,
and medical teams. You will use rigorous quantitative reasoning to
analyze and design experiments that allow us to understand more
deeply, troubleshoot, and improve our existing and future assays.
You will combine clinical and genomic data to gain novel insight
into the interaction between pathogens and disease. This role sits
at the heart of where important decisions are made about our
technology, and a creative and energetic candidate will have the
opportunity to shape the future of our assays and infectious
Why Should You Join Us?
Karius aims to conquer infectious diseases through innovations
around genomic sequencing and machine learning. The companys
platform is already delivering unprecedented insights into the
microbial landscape, providing clinicians with a comprehensive test
capable of identifying more than a thousand pathogens directly from
blood, and helping industry accelerate the development of
therapeutic solutions. The Karius test we provide today is one of
the most advanced solutions available to physicians who aim to
deliver better care to many otherwise ineffectively treated
patients. Our test is the result of some incredible work done by
our scientists, statisticians, engineers, and physicians, all
driven by the same mission. You, as part of the Karius team, will
be able to see how directly your work has a life-changing impact on
people, and at scale.
Reports to: Manager, Bioinformatics
Location: Redwood City, CA
Generate hypotheses, design experiments, and glean insights that
improve the understanding of the genomic signatures of pathogen
Lead the design and implementation of algorithms and statistics and
machine learning models to drive discovery and interpretation using
genomic, metagenomic, and other kinds of biological and clinical
Produce robust, reproducible research findings out of multiple
sources of heterogeneous data.
Collaborate with the scientists, physicians, and engineers to make
meaningful contributions to scientific discoveries and the
invention of technologies.
Whats Fun About the Job?
Karius is operating at the edge of what is now known to be possible
in infectious disease diagnostics. With that, comes a wave of new
and incredible challenges and opportunities. To deliver on that
value, you will be tapping into some of the most advanced
technologies, architecting and innovating where the current
solutions simply don't suffice. You will get to see how much your
work really matters.
Subject to extended periods of sitting and/or standing, vision to
monitor and moderate noise levels. Work is generally performed in
an office environment.
Ph.D. in computational biology, statistics, or related fields.
5-8 years related experience; may include post doctoral
Biotech experience, or equivalent, a plus.
Demonstrated expertise in analysis and visualization of biological
data to drive insight and decision-making.
Experience with and understanding of modern statistics and/or
Familiarity and experience with bioinformatics tools, approaches
and workflows, particularly those related to next-generation
sequencing data analysis.
Familiarity with a range of relevant laboratory techniques (either
through hands-on work or from collaborations with
laboratory-focused colleagues).Proficiency in working with
large-scale datasets in Python or R.
Creativity in generating hypotheses and proposing experiments and
analyses to test them.
Passionate, purpose-driven, and excited about Karius mission.
Excellence at communication and collaboration within a
Detail oriented with exceptional organizational and time management
Self-starting mentality and ability to drive results.
Comfortable working in an environment which combines both research
aspects as well as development.
Ability to work effectively and efficiently in a fast paced
At Karius, we value a diverse and inclusive workplace and provide
equal employment opportunity for all applicants and employees and
are committed to honor and invest in the full diversity of people,
in our hiring, recruiting and development of employees across the
Company. All qualified applicants for employment are encouraged to
apply and will be considered without regard to an individuals race,
color, sex, gender identity and gender expression (including
transgender individuals who are transitioning, have transitioned,
or are perceived to be transitioning to the gender with which they
identify), religion, age, national origin or ancestry, citizenship,
physical or mental disability, medical condition, family care
status, marital status, domestic partner status, sexual
orientation, genetic information, military or veteran status, or
any other basis protected by federal, state or local laws. If you
are unable to submit your application due to a disability, please
contact us at email@example.com and we will accommodate
qualified individuals with disabilities.
Keywords: Karius, Redwood City , Sr. Investigational Computational Biologist, Other , Redwood City, California
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