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Staff Scientist, Reagent Development (Sustain & Support)

Company: Guardant Health, Inc.
Location: Redwood City
Posted on: May 3, 2021

Job Description:

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360, Guardant360 CDx and GuardantOMNI tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early-stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection.

To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Scientist to lead the execution of sustaining and troubleshooting activities pertaining to our launched assays for rare variant studies with next-generation sequencing. At Guardant, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.

Duties and Responsibilities:

* Identify areas for improvement in assay and propose and implement solutions * Design and perform experiments to continually improve our assay workstreams * Develop and perform longitudinal analytics of clinical lab performance and provide regular updates to cross-functional teams * Write experiment reports and update SOPs as needed * Collaborate cross-functionally with operations, process engineering, and bioinformatics to facilitate effective delivery sustaining and support deliverables * Lead in troubleshooting efforts with our Operations teams and capture lessons learned * Manage the escalation process between Operations and Technology teams * Conceptualize and perform feasibility studies on new assay improvements * Ensure all work is performed and documented in compliance with applicable regulatory and quality practices (FDA, ISO1348, CAP/CLIA) * Be a mentor to grow junior team members * Present data, proposals, and progress in various forums and to technical and non-technical audiences * PhD degree in molecular biology, biomedical sciences, bioinformatics, genetics, biochemistry, or related field * Strong foundation in molecular biology techniques and NGS assay development, exemplified by publications, patent applications, or previous product development experience * Strong data analysis skills with experience with Python and R and the experience in handling large datasets * Demonstrated ability to organize, document and communicate scientific data * Consummate team player: demonstrated ability to contribute in an environment where numerous contributions are required to accomplish complex goals. Enjoy working independently and collaboratively in a fast-paced environment and able to adapt to change * Highly motivated and responsible self-starter and independent problem solver * Support troubleshooting activities within the clinical lab with support for ongoing technologies after they are transferred * Comfortable working in a production environment, where quick resolution of issues is key * Excellent interdisciplinary communication skills required * Good organization skills, and detailed orientated * Curiosity and drive * Experience with liquid handling platforms is a plus * Sense of humor is a must

Preferred Skills:

* 6+ years of industry work experience preferred * Product development in a regulated environment * Experience with assay development for automated liquid handling platforms * Experience in sustaining development or support

Employee may be required to lift routine office supplies up to 20 lbs and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Please visit our career page at: http://www.guardanthealth.com/jobs/

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

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Keywords: Guardant Health, Inc., Redwood City , Staff Scientist, Reagent Development (Sustain & Support), Other , Redwood City, California

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