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Staff Research Associate, Reagent Development

Company: Guardant Health, Inc.
Location: Redwood City
Posted on: May 3, 2021

Job Description:

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360, Guardant360 CDx and GuardantOMNI tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early-stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection.

To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Senior or Staff Research Associate to help develop, test, and improve sample preparation technologies for rare variant and epigenetic studies with next-generation sequencing. At Guardant, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.

As a Senior or Staff Research Associate supporting product and technology development, you will work with members within the team and interface with multiple teams including process engineering, clinical operations, research operations, and bioinformatics. You will be hands on in the lab and be required to design, implement, and validate new technologies related to liquid biopsy sequencing assays for the early detection, treatment, and monitoring of all cancer types.

Essential Duties and Responsibilities:

  • Operate next generation sequencing instruments
  • Run sequencing sample preparation assays in medium to high throughput environment
  • Test and improve new sequencing sample preparation assays
  • Log and track research samples throughout sequencing workflow
  • Maintain appropriate inventory of lab supplies
  • Bring a can do attitude to solve new and challenging problems in a high pace environment
  • Analyze data and troubleshoot issues within the tech dev team and among other teams
  • Collaborate with all functions within project teams
  • Engage in early design of products and perform experiments both independently and under the supervision of Senior team members within Tech Dev and Bioinformatics groups
  • Be able to present updates, write reports and SOPs, and contribute to technical discussions
  • A minimum of 6 years of related experience
  • The ability to handle biological samples (i.e. tissue, biofluid, etc) is a must
  • Excellent written and oral communication skills is a must
  • Professional hands-on experience in industrial setting in genomics field is a plus (operational experience is preferred)
  • Experience with development under FDA regulated environment is a plus
  • Hands-on experience in NGS based library preparation, target enrichment, and running sequencing platforms and assays is a plus
  • Experience with process automation for nucleic acid extraction and sample preparation is a plus
  • Experience with data analysis in JMP, R, and python is a plus
  • Local candidates in San Francisco Bay area are preferred.

Education:

BSc, MSc or Ph.D. in Molecular Biology, Bioengineering, Biochemistry or related field

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Keywords: Guardant Health, Inc., Redwood City , Staff Research Associate, Reagent Development, Other , Redwood City, California

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