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Research Associate

Company: Planet Pharma
Location: Redwood City
Posted on: January 7, 2022

Job Description:

Research Associate, Cancer Cell & Systems Biology
The Opportunity:
As a key member in our Biology team, you will:
Be a critical contributor to mechanistic biology and precision medicine research fundamental to the discovery of novel anti-cancer agents.
Utilize pharmacologic and genetic approaches, including CRISPR gene editing, to characterize key oncogenic signaling pathways in order to establish molecular mechanisms underlying response to targeted cancer therapies.
Maintain cultures of multiple human cancer cell lines and CRISPR-engineered cell lines simultaneously to support experimental efforts.
Perform molecular biology/bioassays to interrogate effects of inhibitors on cellular pathways - PCR, qPCR, DNA/RNA preparation, Sanger sequencing, cloning, SDS-PAGE/Western blot, MSD etc.
Prepare next-generation sequencing libraries for targeted gene panels (DNA and RNA) and operate Illumina sequencer.
Develop and perform plate-based cellular assays using reagent kits (experience with assay automation/robotic liquid handlers would be a plus).
Analyze data using data analysis software: Excel, GraphPad Prism, and Softmax Pro.
Be an excellent team member, collaborator, communicator.
Have an eagerness to learn new techniques.
Required Experience, Skills, and Education:
Bachelor's degree or Master's degree in Molecular Biology, Biochemistry, Biology, Genetics, or related field.
2+ years of experience in cell culture/molecular biology role in biotech or academic lab.
Hands-on experience beyond laboratory coursework with demonstrated proficiency in a variety of cellular and molecular biology techniques (e.g. mammalian cell culture, SDS-PAGE/Western blot, PCR, qPCR, kit-based assays such as CTG, AlphaScreen, MSD).
Desire to learn and develop functional genomics approaches for applications in oncology.
Rigorous, quantitative, attention to detail, keen to maximize efficiency.
Highly organized, detail-oriented, excellent record keeping skills, and calm under pressure.
Demonstrated ability to meet project deadlines and work efficiently in a fluid environment.

Keywords: Planet Pharma, Redwood City , Research Associate, Other , Redwood City, California

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