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Research Associate II, Reagent Development

Company: Guardant Health
Location: Redwood City
Posted on: January 15, 2022

Job Description:

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360 -, Guardant360 CDx and GuardantOMNI - tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early-stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection.

Job Description

To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Research Associate to perform laboratory duties, as well as help develop, test and validate novel technologies for rare variant studies with next-generation sequencing. At Guardant, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.

As a Research Associate II in the Technology Development team, you will work with our laboratory manager to maintain laboratory equipment as our laboratory scales. Moreover, you will collaborate cross-functionally with members of technology development and clinical operations to perform NGS experiments. You will be hands-on in the lab, participating in efforts to develop, implement, validate, and transfer assays to our clinical lab. You will participate in teams supporting the maintenance of IVD, IUO, RUO, and LDT products and ensure all work is performed and documented in compliance with applicable regulatory and quality practices (FDA, ISO 13485). An ideal candidate would have some level of knowledge with NGS assay development and good documentation practice (GDP).

Essential Duties and Responsibilities:
Operate molecular biology laboratory equipment including automated liquid handlers, quantitation instruments, thermal cyclers, and next generation sequencing instruments.
Strong understanding in molecular biology techniques, with preferred experience in the areas of NGS.
Demonstrated ability to organize, document and communicate scientific data.
Sense of humor is a must.
Team player: demonstrated ability to contribute in an environment where numerous contributions are required to accomplish complex goals.
Quantitative/analytical mindset- ability to segment complex problems into fundamental parts/basic. principles, develop models and execute experimental tests.
Curiosity and drive for continuous improvement.
Collaborate cross-functionally to assist with drafting and executing test method/process validations.

BA/BS in Molecular Biology, Bioengineering, Biochemistry, or related field.
A minimum of 2 years of experience in industry or related field
The ability to handle biological samples (i.e. tissue, blood, biofluid, etc.)
Willing to do manual, repetitive lab work.
Excellent written and oral communication skills.
Knowledge of GDP.
Experience with process automation for nucleic acid extraction, NGS sample preparation assays, and sequencing platforms.
Laboratory position: Local candidates in San Francisco Bay surrounding area are preferred.

Additional Information

Covid Vaccination Policy: Starting January 7, 2022, Guardant Health will require all employees to be fully vaccinated to either (a) establish that they have been fully vaccinated against COVID-19; or (b) request and obtain an approved exemption from Guardant's COVID-19 U.S. Vaccination Policy as a reasonable accommodation. An employee is considered fully vaccinated against COVID-19 two weeks after receiving the second dose of a two-dose vaccine or one dose of a single-dose vaccination. Acceptable vaccines are approved or under emergency use authorization by the U.S. Food and Drug Administration (FDA) and/or the World Health Organization (WHO). In addition, fully-vaccinated employees will be required to maintain their fully-vaccinated status under this Policy by obtaining, if applicable, any FDA-approved boosters.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment. Ability to sit for extended periods of time.

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

Please visit our career page at:

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants .

Keywords: Guardant Health, Redwood City , Research Associate II, Reagent Development, Other , Redwood City, California

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