Principal Systems Architect Mechanical Engineer

Company: GenapSys
Location: Redwood City
Posted on: January 16, 2022

Job Description:

Principal Systems Architect Mechanical Engineer SUMMARY:

• At GenapSys we are working to power the world of healthcare and diagnostics with advanced DNA sequencing technology.
• Our sequencing instrument platform leverages a proprietary electrical microfluidic sequencing chip with a scalable number of detectors, enabling a wide range of applications including targeted sequencing in oncology, pharmacogenomics and genome-wide sequencing in microbiology and others.
• We believe in a world where every researcher has a compact, scalable, and affordable sequencer in their own lab, empowering the democratization of genetic sequencing.
• Our novel sequencing method is revolutionizing genomics discovery, biomedical research, healthcare, diagnostics, agriculture, and a variety of other fields. ABOUT THE ROLE:
  • The Principal Systems Architect Mechanical Engineer will play an exciting and very important role within the R&D Instrumentation Engineering Team.
  • This position will lead, direct, and coordinate, and collaborate in the design of new GenapSys DNA Sequencing instrument platforms. RESPONSIBILITIES:
    • Directly responsible for the top, systems-level, architectural design of new sequencing instruments to meet strict performance, size, cost, manufacturability, and reliability requirements.
    • In collaboration with design engineering, cross functional stakeholder, and executive teams:
      • Drive for clear definition of requirements and scope
      • Lead generation and evaluation of design concepts
      • Identify constraints, risks, and areas requiring investigation
      • Define tests to answer key questions, mitigate risks, and demonstrate proof of concepts
      • Drive for consensus in concept selection
      • Define module interfaces and interfaces between mechanical, electrical, firmware, software, reagent, and user interfaces
      • Work closely with mechanical, electrical, firmware, and software engineers, as well as reagent and assay development team members, to deliver cohesive prototype and commercial designs for instruments and consumables.
      • Use sound judgment, creativity, intuition, and experience with disciplined approaches to assess and mitigate risks while meeting aggressive timelines.
      • Create clear, effective documentation, including requirements, block diagrams, specifications, cost analysis, engineering analysis, drawings, fluidic schematics, BOMs, test cases/reports, presentations, and traceability matrices.
      • Provide technical leadership in project planning. QUALIFICATIONS:
        • 12+ years of relevant post-academic experience
        • 5+ years direct experience as a Systems Architect with above responsibilities
        • Bachelor's degree in mechanical engineering, mechatronics, or systems engineering
        • Experience translating broad, complex requirements into simple, compact, easy to use, low cost, manufacturable, and reliable designs
        • Able to quickly conceive multiple design options, communicate trade-offs, and lead consensus
        • Fully proficient in using Solidworks to create concept cartoons, detailed mechanical designs, and drawings, including appropriate definition of critical dimensions and tolerances
        • Broad knowledge of fabrication processes, tolerances, and corresponding typical applications, including, but not limited to: machining, sheet metal, plastic injection molding, and casting
        • Excellent communication skills and initiative
        • A record of delivering on commitments in busy, fast-paced environments DESIRED QUALIFICATIONS
          • Master's degree in mechanical engineering, mechatronics, or systems engineering
          • A breadth and depth of experience bringing similar small-scale, life science, laboratory instrumentation products and consumables from concept through successful commercialization
          • Has developed systems that precisely move fluid on the micro scale (ID - 500 micron), including control and management of flow rate, bubbles, leaks, and carryover contamination
          • Understands pneumatics, temperature control, actuating mechanisms, PCBA packaging, custom plastic and metal parts, structures, motor control, and enclosures (skins)
          • DOE and DOE tools (e.g., Minitab).
          • Working under a phased gate, Product Development Process (PDP).
          • Development under ISO 13485 compliant QMS systems. WHAT WE OFFER (US BASED-EMPLOYEES):
            • Competitive compensation and generous stock options.
            • Comprehensive, industry-leading medical, dental and vision benefits for employees and dependents.
            • Pre-tax savings plans for health care, childcare, elder care, public transportation, and parking expenses.
            • 401(k) retirement plan with matching employer contribution.
            • Free daily catered gourmet lunches and snacks.
            • For those emergency moments - long- and short-term disability, life insurance (2x salary) and an employee assistance program.
            • Work with driven and enthusiastic colleagues in a fast-paced and entrepreneurial environment, the opportunity to work on problems that matter in a highly collaborative environment. req21-01194Job Requirements:
              • Directly responsible for the top, systems-level, architectural design of new sequencing instruments to meet strict performance, size, cost, manufacturability, and reliability requirements.
              • In collaboration with design engineering, cross functional stakeholder, and executive teams:
                • Drive for clear definition of requirements and scope
                • Lead generation and evaluation of design concepts
                • Identify constraints, risks, and areas requiring investigation
                • Define tests to answer key questions, mitigate risks, and demonstrate proof of concepts
                • Drive for consensus in concept selection
                • Define module interfaces and interfaces between mechanical, electrical, firmware, software, reagent, and user interfaces
                • Work closely with mechanical, electrical, firmware, and software engineers, as well as reagent and assay development team members, to deliver cohesive prototype and commercial designs for instruments and consumables.
                • Use sound judgment, creativity, intuition, and experience with disciplined approaches to assess and mitigate risks while meeting aggressive timelines.
                • Create clear, effective documentation, including requirements, block diagrams, specifications, cost analysis, engineering analysis, drawings, fluidic schematics, BOMs, test cases/reports, presentations, and traceability matrices.
                • Provide technical leadership in project planning.

Keywords: GenapSys, Redwood City , Principal Systems Architect Mechanical Engineer, Other , Redwood City, California