Company: System One
Location: Redwood City
Posted on: January 16, 2022
Title: Research Scientist
Location: Redwood City, CA
Start date: ASAP
The key responsibilities include molecular biology and cell line
generation for antigens and bio-therapeutic products. We design and
develop antigen cell lines for mice immunization, binder screening,
cell-based binding and function assays, and in vivo tumor models.
Also, we develop cell lines for the expression of bio-therapeutic
products and reagents.
Design and construct vectors (non-viral and Lenti-vectors) for
recombinant protein expression.
Culture host cells and transfect host cells with expression vectors
in different transfection methods.
Perform Lenti-virus production and cell transduction to develop
antigen cell lines.
Characterize and sort cell lines with FACS, sorter, ELISA, western
Screen stable clonal cell lines for bio-therapeutic product and
reagents with growth profile, production rates, and yields.
B.Sc. (+5 years working experience) or M.Sc. (+2 years working
experience) in Cell biology, Immunology, Cancer biology, Molecular
biology, Biochemistry or related fields.
Strong mammalian cell culture, transfection and transduction
experience is necessary.
Hands-on experience with FACS, ELISA and Western Blot is
Basic molecular cloning knowledge and lab skills are needed
Proficient with basic data analysis and visualization software
(Office, Flowjo, Geneious etc.)
Excellent written, oral, and organizational skills.
Motivated self-starter, with the ability to multitask, rational
thinks and problem solving.
Experience with mRNA preparation, production and purification is a
Experience with multiple color FACS analysis and cell sorting is a
Cell line engineering experience via HDR CRISPR/Cas9 is a plus.
The successful candidate is expected to be a good team player with
excellent written and oral communication, and organizational
Joule, a System One division is a leader in specialized workforce
solutions and integrated services. With more than 6,000 employees
and roughly 50 offices throughout the U.S. we provide scientific,
clinical, engineering, energy, IT, legal and administrative
staffing services. For more than 40 years, we have delivered
workforce solutions and integrated services to clients
Keywords: System One, Redwood City , Research Scientist, Other , Redwood City, California
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