Product Development Scientist
Company: Codexis, Inc.
Location: Redwood City
Posted on: May 15, 2022
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Job Description:
Are you ready to join our mission to improve the health of
people and the planet? Do you have a passion for science and the
transformational role that enzymes are playing? Come be part of our
team at Codexis, Inc. We are a leading enzyme engineering company
leveraging our proprietary CodeEvolver - technology platform to
discover and develop novel, high performance enzymes and novel
biotherapeutics.
Our Biotherapeutics division combines bioinformatics with directed
evolution to uniquely tailor next generation biotherapeutics with
transformative properties. We engineer proteins with high efficacy
and safety with the goal of delivering the therapeutic to patients
as an oral biologic, or gene therapy.
We are looking to hire an Associate Scientist/Scientist to join our
Product Development Team
If any of the below describes you, we would love to meet you!
Passionate about large-molecule drug discovery to improve the
quality of life for patients with rare diseases.
Experienced or interested in novel technologies for protein
engineering and directed evolution.
Excited about developing biochemical and biophysical assays and
using extensive laboratory automation to characterize thousands of
protein variants.
In this role you will be responsible for:
Support a cross disciplinary department that will work closely with
other functions such as Molecular Biology, Biochemistry,
Computational Biology, QC, Manufacturing, and Marketing to develop
and validate novel reagents, consumables, and kits for applications
such as DNA amplification, RNA analysis, NGS library preparation
for the expansion of Codexis' molecular diagnostics product
portfolio
Assisting in design and initiation of accelerated and long-term
stability studies to establish high risk reagents/workflow/storage
issues.
Assisting in development, validation, and implementation of new QC
methods for productization of reagents, consumables, and kits
through a variety of analytical and functional tests.
Independently troubleshoot and resolve reagent formulation, QC, and
incoming material issues.
Working with team members to design and conduct product development
studies such as guard banding studies, DOE studies, failure mode
investigation.
Being data driven - critically analyzing and deriving insights from
experimental data using standard and custom bioinformatics tools
and present results internally.
Assisting in technology transfer phase of the product pipeline as
new products move from R&D into Manufacturing in preparation
for commercial launch.
Assisting in study design for customers testing of Codexis'
products; interpreting data and incorporating customer feedback
into optimization and development experiments.
Helping build internal process development infrastructure across
product lines.
Demonstrating exceptional time management skills and a 'can do'
approach to challenges such as changing needs and/or tight
timelines.
Maintaining records/documentation, as well as writing reports and
SOPs as needed
Maintaining a safe and efficient workplace, following safe lab
practices, participating in lab organization, housekeeping, and
weekly maintenance activities
To be successful in this role, your background and experience
should include:
Ph.D. with 2+ years of relevant industry experience in molecular
biology, biochemistry, genetics, microbiology, or related fields.
M.S. with 4+ years of experience will be considered.
Broad working knowledge of molecular biology and the ability to
apply that knowledge towards development of novel workflows.
Previous work experience with successfully launched products is
essential.
The successful applicant should have exceptional attention to
detail and the ability to execute and analyze highly complex
experiments.
Sound understanding of molecular biology techniques including PCR,
RT-qPCR, PAGE, flow cytometry, molecular cloning, nucleic acid
isolation and manipulation, and NGS sample preparation
technologies.
Familiarity with moving products from concept phase through
commercial launch (commercialization phase-gate process).
Ability to develop knowledge base and improve skillsets to
successfully support innovative projects
Attention to detail with excellent organizational, experimental
data recording, and time management skills
Ability to multi-task and adapt with changing needs.
Must be motivated and able to work under tight timelines
Demonstrated ability to write SOPs.
Strong verbal and written communication skills
DESIRED SKILLS
Experience using statistical tools, such as JMP to analyze complex
data sets, create DOE experiments, and data trending.
Experience operating liquid handling robots and other laboratory
automation tools. Experience programming these instruments would be
highly beneficial.
Experience working with microfluidic devices.
Experience with custom reagent vendors and setting up OEM
relationships.
Knowledge of current and evolving trends in the NGS field
What can Codexis offer you? (besides an amazing and collaborative
culture?)
Full benefits your first day
100% match on 401k (up to 4%)
Generous flex time off
Fitness reimbursement
Free fitness classes
Back up child/dependent care
Student loan assistance
Commuter vouchers
PRINCIPALS ONLY
NO AGENCIES OR THIRD PARTIES
Codexis is an equal opportunity employer & prohibits unlawful
discrimination based on race, color, religion, gender, sexual
orientation, gender identity/expression, national origin/ancestry,
age, disability, marital & veteran status.
Keywords: Codexis, Inc., Redwood City , Product Development Scientist, Other , Redwood City, California
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