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Senior Research Associate - Tech Dev

Company: Guardant Health
Location: Redwood City
Posted on: May 16, 2022

Job Description:

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360 -, Guardant360 CDx and GuardantOMNI - tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection.

Job Description

As a Research Associate in the LUNAR Technology Development team, you will work with members of the team and collaborate cross-functionally with members of technology development, bioinformatics, process engineering, automation, clinical development, and operations. You will be hands-on in the lab, leading and participating in efforts to develop, implement, validate, and transfer assays to our clinical lab. You will lead and participate in teams supporting the development of IVD and LDT products. An ideal candidate would have experience with NGS assay development for automated platforms in a regulated environment.Preference is given to candidates with experience developing/optimizing oligonucleotide-based assay methodology including hybrid capture-related methods.
Execute studies aimed at improving and streamlining NGS assays
Collaborate cross-functionally to facilitate the effective transfer of methods and processes to the CLIA lab
Identify areas for improvement in assay work stream and propose and implement solutions
Ensure all work is performed and documented in compliance with applicable regulatory and quality practices (CLIA/CAP, IVD (Design Control), ISO13485)
Present data, proposals, and progress in various forums and to technical and non-technical audiences
Strong foundation in molecular biology techniques including sample preparation for NGS
Quantitative/analytical mindset- ability to segment complex problems into fundamental parts/basic principles, develop models and experimental tests for those models, and synthesize results into actionable solutions
Experience with NGS data analysis tools (Python, R, IGV, etc.)
Demonstrated ability to organize, document and communicate scientific data
Sense of humor is a must
Consummate team player: demonstrated ability to contribute in an environment where numerous contributions are required to accomplish complex goals
Enjoy working independently and collaboratively in a fast-paced environment and able to adapt to change
Curiosity and drive
Experience in the following areas is highly desirable:
Product development in a regulated environment
Experience with assay development for automated liquid handling platforms
Experience with patient specimen handling, particularly whole blood, buffy coat and plasma

Bachelors degree in Molecular Biology, Genetics, Biochemistry or related field and > 2 years of relevant work experience

Masters degree in Molecular Biology, Genetics, Biochemistry or related field and > 1 year of relevant work experience

Additional Information

Covid Vaccination Policy: Starting January 7, 2022, Guardant Health will require all employees to be fully vaccinated to either (a) establish that they have been fully vaccinated against COVID-19; or (b) request and obtain an approved exemption from Guardant's COVID-19 U.S. Vaccination Policy as a reasonable accommodation, as consistent with applicable laws.Anemployee is considered fully vaccinated against COVID-19 two weeks after receiving the second dose of a two-dose vaccine or one dose of a single-dose vaccination. Acceptable vaccines are approved or under emergency use authorization by the U.S. Food and Drug Administration (FDA) and/or the World Health Organization (WHO). In addition, fully-vaccinated employees will be required to maintain their fully-vaccinated status under this policy by obtaining, if applicable, any FDA-approved boosters.

Employee may be required to lift routine office supplies and use office equipment.Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment.Ability to sit for extended periods of time.

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants .

Please visit our career page at:

Keywords: Guardant Health, Redwood City , Senior Research Associate - Tech Dev, Other , Redwood City, California

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