Senior Scientist, Bioinformatics / Repertoire Analysis & Predictions

Company: Bristol Myers Squibb Company
Location: Redwood City
Posted on: January 24, 2023

Job Description:

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: Job DescriptionWe are seeking a creative and collaborative bioinformatician with expertise in next-generation sequencing and immune repertoire analysis to help us discover and develop the next generation of therapeutic antibodies and cellular therapies. You will be responsible for designing and implementing novel computational approaches on next-generation sequencing (NGS) data to identify B-cell and T-cell receptor sequences that can be optimized for protein and cellular therapeutics with desired binding characteristics and biological activity. This role provides the opportunity to work on multidisciplinary teams to solve challenging problems in the discovery and design of new biological and cellular therapies. We are deeply passionate about what we do here at Bristol Myers Squibb because we know that our work helps deliver truly innovative and life-changing therapies for complex diseases of unmet medical need. If this inspires you as well, we're excited to have you join us!RESPONSIBILITIES

• Perform data-mining on proprietary and public antibody sequence and structure databases to derive insights for antibody library design
• Develop computational NGS workflows for antibody library characterization and selections
• Partner with project teams to build pipelines around analytical frameworks for antibody and T-cell receptor repertoire sequencing
• Collaborate with colleagues as part of project teams passionate about developing the next generation of innovative therapeutic antibodies and cell therapies, lending analytics expertise to biological and technical domain matter experts as required
• Present strategies, approaches, results, and conclusions to a publishable standard in static and interactive formats
• Participate in authorship of scientific reports, and present methods and conclusions to publishable standardsBasic Qualifications
  • Bachelor's Degree in structural bioinformatics, computer science, engineering, or similar with 7+ years of academic / industry experience
  • OR Master's Degree in structural bioinformatics, computer science, engineering, or similar with 5+ years of academic / industry experience
  • OR PhD in structural bioinformatics, computer science, engineering, or similar with 2+ years of academic / industry experiencePreferred Qualifications
    • PhD in structural bioinformatics, computer science, engineering, or similar with 2+ years of post-doctoral work or relevant industry experience.
    • Demonstrated ability to derive insights from high-dimensional data with complex patterns using statistical learning approaches using readable, reproducible, and efficient code.
    • Proven track record of contributing to and helping advance multi-disciplinary team projects.
    • Expertise in algorithmic implementation, workflow/pipeline development, statistical programming and data manipulation using middle-level languages or Python/R; contemporary, open-source bioinformatics tools and database structures, collaborative development skills using version control systems (e.g., Git), familiarity with Unix shell and deployment and use of virtualized working environments (e.g., Docker).
    • Scientific curiosity with an ability to identify questions bioinformatics approaches can address, and the skills to develop solutions both independently and collaboratively.
    • Excellent problem-solving skills and teamwork.
    • Strong communication, data presentation, and visualization skills.
    • Knowledge in biochemistry or protein engineering is a plus.The starting compensation for this jobis a range from $109,000-$150,700, plus incentive cash and stock opportunities (based on eligibility).The starting pay rate takes into account characteristics of the job, such as required skills and the where the job is performed.Final individual compensation will be decidedbased on demonstratedexperience.For more on benefits, please visit our . Eligibility for specific benefits listed on our BMS Careers site may vary based on the job and location.Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Bristol Myers Squibb Company, Redwood City , Senior Scientist, Bioinformatics / Repertoire Analysis & Predictions, Other , Redwood City, California