Genomics Translational Research Senior Scientist

Company: Bristol Myers Squibb Company
Location: Redwood City
Posted on: January 27, 2023

Job Description:

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: When you join BMS, you are joining a diverse, high-achieving team united by a common mission.The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapies. Comprised of scientists across multiple disciplines, we are responsible for the biology and translational science necessary to support drug development from target identification through to first-in-human studies.Position Summary:We are seeking a highly motivated and experienced individual with genomics expertise to join the TME TRC Translational Research team at Bristol Myers Squibb in Redwood City, CA. As a member of the NGS team, the successful candidate will perform and develop NGS workflow assays to support biomarker identification and target discovery. The successful candidate will be responsible for the development, optimization, and execution of NGS processes including bulk or single cell transcriptomic, genomic, and epigenomic sequencing platforms. As a key contributor to translational research teams, the candidate will apply genomic methods to inform indication prioritization and pharmacodynamic biomarker discovery and develop prototype biomarker assays for implementation in clinical trials.Position Responsibilities:In the role as a Senior Scientist within the TME TRC Translational Research team, the ideal candidate:

• Accountable for design of hypothesis-driven studies using genomic technologies to inform pharmacodynamics, mechanism of action, and patient stratification/selection.
• Develops, validates, and applies NGS methods for various genomic, epigenomic and transcriptomic sequencing platforms.
• Independently plans and executes routine genomic assays. Independently analyzes data, troubleshoots, and determines next steps, and communicates results and timelines to project teams.
• Draft SOW and manage CRO-based genomic studies to ensure the timely completion of outsourced activities.
• Partner closely with translational biomarker, bioinformatics, and discovery biology scientists to drive the advancement of therapeutic candidates.
• Play a key role in providing the relevant translational input to discovery and translational projects as part of interdisciplinary teams.Experience = Basic Qualifications:
  • Bachelor's Degree
    • 7+ years of academic and / or industry experienceOr
      • Master's Degree
        • 5+ years of academic and / or industry experienceOr
          • Ph.D. or equivalent advanced degree in the Life Sciences
            • 2+ of academic and / or industry experiencePreferred Qualifications:
              • Strongly prefer PhD with either 2+ years of significant biopharmaceutical industry experience or postdoc in genomics field, or MS with 8+ years of relevant experience in genomics research in biopharmaceutical industry.
              • Previous experience in cancer biology or immuno-oncology with translational research experience highly preferred.
              • Requires extensive experience performing genomic assays including RNA preparation, qPCR, NGS library prep, and Nanostring analysis.
              • Familiarity with biomarker assay development (tumor tissue-based and peripheral genomics and transcriptomics) to guide experimental prioritization is preferred.
              • Proven track record of handling multiple high priority tasks in parallel with internal and external collaborators including CRO's and academics.
              • Excellent verbal and written communication skills across all levels both within an organization and with external collaborators/companies with the ability to recognize, articulate, and accept calculated risks to make informed decisions.
              • Comfortable working in a collaborative manner in a fast-paced environment.
              • Willing to work as a topic expert, outside of a traditional functional environment, in a team unified around serving the assets.The starting compensation for this job is a range from $109,000.00 - $150,700.00, plus incentive cash and stock opportunities (based on eligibility).The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience.For more on benefits, please visit our BMS Careers site.Eligibility for specific benefits listed in our careers site may vary based on the job and location.BMSONCRD, BMSDDTMRCA#LI-OnsiteAround the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visitto access our complete Equal Employment Opportunity statement.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Bristol Myers Squibb Company, Redwood City , Genomics Translational Research Senior Scientist, Other , Redwood City, California