Scientist, Cancer Biology Research

Company: Bristol-Myers Squibb
Location: Redwood City
Posted on: March 20, 2023

Job Description:

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: When you join BMS, you are joining a diverse, high-achieving team united by a common mission.The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapies and transforming response and durability rates for cancer patients. Comprising of scientists across multiple disciplines we are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.Position Summary:We are seeking a Scientist to join the Cancer Biology research team within the Tumor Microenvironment Thematic Research Center at Bristol Myers Squibb in Redwood City, CA. The qualified candidate will aid in the advancement of early-stage therapeutic targets at the intersection of tumor genetics and immuno-biology. The Cancer Biology team is composed of experts in tumor-intrinsic biology, functional genomics, and immune-oncology who develop therapies that leverage the interplay between the host and tumor. Our mission is to provide transformative therapeutics to cancer patients that improve response rates and durability to this challenging disease.Position Responsibilities:In the role as a Scientist within the TME TRC Cancer Biology team, the ideal candidate:

• Collaborates with colleagues in the oncology, immuno-oncology, in vivo pharmacology, and medicinal chemistry groups to advance preclinical drug development programs from target identification through lead optimization
• Designs and executes experiments by adapting standard methods and applying breadth of knowledge and prior work experience
• Performs low-throughput assays using experimental small molecules and/or biologics to determine mechanism of action
• Makes decisions that impact entire project team
• Contributes to the improvement and development of new approaches
• May represent project team or sub-team by presenting work in multidisciplinary meetingsExperience =Basic Qualifications:
  • Bachelor's Degree
  • 5+ years of academic and / or industry experienceOr
    • Master's Degree
    • 3+ years of academic and / or industry experienceOr
      • Ph.D. or equivalent advanced degree in the Life Sciences
      • No experience necessaryPreferred Qualifications:
        • Strongly prefer Ph.D. with 0-3 years postgraduate experience, M.S. with 3-5+ years OR B.S. with 5-8+ years of experience in cancer biology or cellular and molecular biology. Industrial experience and/or scientific knowledge of immunology/immuno-oncology is preferred.
        • Required technical expertise:
        • - Cell culture: cancer cell line propagation and qualification, BSL2+ and lentiviral production/transduction
        • - mRNA analysis: RNA purification/qualification, cDNA synthesis, Taqman qPCR
        • - Protein characterization: western blotting, ELISA
        • - Molecular biology: gene synthesis (outsourced) and electroporation/transfection, PCR, primer design, amplicon production and submission for Sanger sequencing
        • - CRISPR/Cas9/sgRNA: design and production of stable knock-out cell lines using electroporation or lentiviral transduction.
        • - Computation: proficiency in Microsoft Office, Prism and Flowjo for data analysis and figure generation
        • Preferred technical expertise:
        • - Primary cells: isolation, propagation, and phenotyping of immune cells from mouse or human
        • - Flow: design and use of multicolor panels for analysisThe starting compensation for this job is a range from $97,000.00 - $135,300.00, plus incentive cash and stock opportunities (based on eligibility).The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience.For more on benefits, please visit our BMS Careers site.Eligibility for specific benefits listed in our careers site may vary based on the job and location.BMSONCRDBMSDDTMRCA#LI-OnsiteIf you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as "Transforming patients' lives through science--- ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolPhysical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.COVID-19 InformationTo protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation.Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment.This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.BMS is dedicated to ensuring that people with disabilities can perform complex functions through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Bristol-Myers Squibb, Redwood City , Scientist, Cancer Biology Research, Other , Redwood City, California